Research

SMIRG at RSNA 2007

Abstract of oral presentations by SMIRG at the 93nd congress of Radiological Society of North America (RSNA 2007).

 

 

 

 Fri Nov 30 2007 11:50AM - 12:00PM ROOM E353B

Dynamic Examination of Penis: Usefulness of Study of Intracavernous Vascularization and Individuation of Anatomical Variants by Color Doppler Echotomography and High Sensitivity Color Doppler Energy

V A Migaleddu, MD, Sassari, Sardinia ITALY; G Virgilio, MD; R Prost, MD; D Scanu, MD; D Sirigu, MD; G Campisi, MD

PURPOSE

To check the usefulness of color Doppler and high sensitivity color Doppler Energy in the study of intracavernous vascularization and in detecting anatomical variants.

METHOD AND MATERIALS

Sequoia 512 imagegate (Siemens-Acuson) equipment was used with a high frequency probe (14 Mhz and Doppler 13 Mhz) to consecutively examine 33 patients for erectile deficit; an initial morphological study preceded the functional color Doppler study and color Doppler Energy after intracavernous injection of 10 mcg of alprostidil. Individuation of the cavernous artery or its anatomical variants was preliminary to placing the sample volume for velocytometric assessment.

RESULTS

Of 56 patients (aged 32-71) 12 patients (21.4%) were found to have anatomical variants of the cavernous artery (C.A.): 8 with double C.A. and 1 with triple C.A. In 3 cases shunts between C.A. and bulbar artery were identified and between cavernous artery and pudendal artery.

CONCLUSION

Individuation of anatomical variants in intrapenal vessels enables the sample volume to be placed as near as possible to the origin of the C.A., permitting a reliable velocytometric evaluation. Velocytometric readings in the distal portions of the cavernous artery, particularly in the presence of anatomical variants, tend to underestimate velocity.

CLINICAL RELEVANCE/APPLICATION

Anatomical variants of intrapenal vessels are not well known; correct ultrasound dynamic examination requires an accurate detection.


 

Tue Nov 27 2007 12:15PM - 1:15PM ROOM Lakeside Learning Center

H-MRI Spectroscopy: Urine Profile of Children with Diabetes Type 1

N Culeddu, BMBCh; V A Migaleddu, MD, Sassari, Sardinia ITALY; M Chessa, BMBCh; P Fresu, MD; G Meloni, MD; G Virgilio, MD

PURPOSE

H-MRI spectroscopy of biofluids provides a wealth information on the metabolic processes in human body. Spectra are very complex and in order to focus on significant difference between a set of spectra from control and from humans with disease chemometric methods are used. NMR combined with pattern recognition has been shown to be useful in diagnosis of significant health problem like coronary heart disease, Alzheimer and Parkinson disease. Diabetes type 1( Insulin dependent ) is endemic in Sardinian people, with an incidence five greater of rest of Europe .The aim of our study is to characterize metabolic profile of urine from children affected and from controls.

METHOD AND MATERIALS

NMR spectrum are obtained with 600 MHz spectrometer Bruker (Bruker BioSpin GmbH Rheinstetten, Germany. PCA (SPSS Inc. Headquarters, Chicago, Illinois) was performed on a H1 spectra dataset obtained after bucketing integration using Amix (Bruker).

RESULTS

37 samples of urine from healthy and diabetic childrens are anaizued: PCA doesn’t lead significative results, despite great reduction of data (from 140 variables to 5 functions) LDA leads a goood separation with only one discriminant function to well separate datasets >90% of recognizing data.

CONCLUSION

Consistent differences in the urinary metabolite profiles of children with diabete Type I were identified with a NMR-based metabonomic strategy. Furthermore, a SPSS model based on the 1H NMR-spectral profiles allowed characterization and prediction of healty and diabetic childrens. These findings highlight the potential of metabonomics as a novel approach for fundamental investigations in metabolic diseases studies.

CLINICAL RELEVANCE/APPLICATION

Metabolite-targeted MR imaging technique should be useful in early stage diagnosis.


 

Intrahepatic Vascular Shunts: Ultrasound and Doppler Features

M Bertolotto, MD, Trieste, ITALY; C Martinoli, MD; V A Migaleddu, MD; S Cernic; M Coss, MD; M A Cova, MD

PURPOSE/AIM

The appearance at color Doppler US of all different types of intrahepatic vascular communications is described and illustrated referring to vascular remnants of the embryonic development and to a variety of pathological changes of liver vasculature

CONTENT ORGANIZATION

  1. Introduction
  2. Embryologic development of hepatic vessels
  3. Arterioportal shunts
  4. Arteriosystemic venous shunts
  5. Portosystemic venous shunts
  6. Systemic-to-systemic venous shunts
  7. Portal-to-portal venous shunts
  8. Conclusion
  9. References

SUMMARY

All types of intrahepatic vascular shunts can be identified and characterized at US. Arterioportal and arteriosystemic venous shunts are seen in normal and cirrhotic livers, after traumas, within tumors and nontumoral AV malformations. Portosystemic venous shunts are persistent communications between vitelline veins due to focal absence of sinusoids. Systemic-to-systemic shunts are seen in chronic hepatic venous congestion and Budd-Chiari syndrome. Portal-to-portal venous shunts are very rare.