Lectures

Focal liver lesion: nonlinear contrast-enhanced ultrasound imaging

References

  1. Abbey-Toby, A., Cazals-Hatem, D., Colombat, M., Belghiti, J., Vilgrain, V. and Degott, C. 2003. Inflammatory pseudo-tumor of the liver: is pre-operative diagnosis possible? Gastroenterol. Clin. Biol. 27:883-90.

  2. Akahn, O., and Pringot, J. 2002. Imaging of abdominal tubercolosis. Eur. Radiol. 12: 321-323.

  3. Albrecht, T., Hoffmann, C.W., Schmitz, S.A., Schettler, S., Ovemberg, A., Germen, C.T., and Wolf K.J. 2001. Phase-inversione sonography during the liver-specific late phase of contrast enhancement: improved detection of liver metastases. Am. J. Roentgenol. 176 (5): 1191-1198.

  4. Albrecht, T., Blomley, M.J., Burns, P.N., Wilson, S., Harvey, C.J., Leen, E., Claudon, M., Calliada, F., Correas, J.M., LaFortune, M., Campani, R., Hoffmann, C.W., Cosgrove, D.O., and LeFevre, F. 2003. Improved detecion of hepatic metastases with pulse-inversion US during the liver-specific phase of SHU 505A: multicenter study. Radiology 227: 361-370.

  5. Albrecht, T., Oldenburg, A., Hohmann, J., Skrok, J., Hoffmann, C.W., Schettler, S., and Wolf, K.J. 2003. Imaging of liver metastases with contrast-specific low-MI real-time ultrasound and SonoVue. Eur. Radiol. 13 (Suppl 3): 79–86.

  6. Albrecht, T., Hohmann, J., Oldenburg, A., Skrok, J., and Wolf, K.J. 2004. Detection and characterisation of liver metastases. Eur. Radiol. 14 (Suppl 8) 25-33.

  7. Apfel, R.E., and Holland, C.K. 1991. Gauging the likelihood of cavitation from short-pulse, low duty cycle diagnostic ultrasound. Ultrasound. MedBiol. 17: 175-185.

  8. Bartolozzi, C., Cioni, D., Donati, F., and Lencioni, R. 2001. Focal liver lesions: MR imaging-pathologic correlation. Eur. Radiol. 11: 1374-1388.

  9. Bleuzen, A., and Tranquart, F. 2004. Incidental liver lesions: diagnostic value of cadence contrast pulse sequencing (CPS) and SonoVue. Eur. Radiol. 14 (Suppl 8): 53-62.

  10. Brauner, M., Buffard, M.D., Jaentils, V., Legrand, I., and Gotheil, C. 1989. Sonography and computed tomography of mocroscopic tuberculosis of the liver. JClin. Ultrasound 17: 563-568.

  11. Brú, C., Marotto, A., Bruix, J., Faus, R., Biachi, L., Calvet, X., Ayuso, C., Vilana, R., Gilalbert, R. and Rodes, J. 1989. Diagnostic accurancy of fine-needle biopsy in patients with hepatocellular carcinoma. Dig. Dis. Sci. 34:1765-1769.

  12. Bruix, J., and Sherman, M., 2005. Management of Hepatocellular carninoma. J. Hepatology 42: 1208-1236.

  13. Bruix, J., Sherman, M., Llovet, J.M., Beaugrand, M., Lencioni, R., Burroughs, A.K., Christensen, E., Pagliaro, L., Colombo, M. and Rodes, J. 2001. Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona. EASL Conference. J. Hepatology  35: 421-430.

  14. Burns, P.N., Wilson, S.R. and Simpson, D.H. 2000. Pulse inversion imaging of liver blood flow: an improved method for characterization of focal masses with microbubble contrast. Invest. Radiol.  35: 58-71.

  15. Catalano, O., Nunziata, A., Lobianco, R., and Siani, A. 2005. Real-time harmonic contrast material-specific US of focal liver lesions. RadioGraphics 25: 333-349.

  16. Chin C.T., and Burns P.N. 1997. Predicting the acoustic response of a microbubble population for contrast imaging. In: IEEE Ultrason. Symp.: 1557-1560.

  17. Clarke, M.P., Kane, R.A., Steele, G. Jr., Hamilton, E.S., Ravikumar, T.S., Onik, G. and Clouse, M.E. 1989. Prospective comparision of pre-operative imaging and intraoperative ultrasonography in the detecion of liver tumours. Surgery 106: 849-855.

  18. Conlon, R., Jacobs, M., Dasgupta, D., and Loge, J.P. 2003. The value of intraoperative ultrasound during hepatic resection compared with improved preoperative magnetic resonace imaging. Eur. Ultrasound 16: 211-216.

  19. Cosgrove, D.O. 2001. Malignant liver disease. In: Meire HB, Cosgrove DO, Dewbury KC, Farrant P. (eds) Clinical Ultrasound a Comprehensive Text. Abdominal and General Ultrasound, vol. 1, 2nd ed. Churchill Livingstone, London, 211-231.

  20. Cosgrove, D.O., Harmonic imaging: Tissue and microbubbles.

  21. De Baere, T., Elias, D., Dromain, C., Din, M.G., Kuoch, V., Ducreux, M., Boige, V., Lassau, N., Marteau, V., Lasser, P., Roche, A. 2000. Radiofrequency ablation of 100 hepatic metastases with a mean follow-up of more than 1 year. Am.  J.  Roentgenol. 175:1619-1625.

  22. Dodd, G.D. 3rd., Soulen, M.C., Kane, R.A., Livraghi, T., Lees, W.R., Yamashita, Y., Gillams, A.R., Karahan, O.I., and Rhim, H. 2000. Minimally invasive treatment of malignant hepatic tumors: at the threshold of a major breakthrough. Radiographics 20: 9-21.

  23. EFSUMB Study Group Albrecht, T., Blomley, M., Bolondi, L., Claudon, M., Correas, J.M., Cosgrove, D., Greiner, L., Jager, K., Jong, N.D., Leen, E., Lencioni, R., Lindsell, D., Martegani, A., Solbiati, L., Thorelius, L., Tranquart, F., Weskott, H.P., Whittingham, T. 2004. Guidelines for the Use of Contrast Agents in Ultrasound . UltraschallMed. 25: 249-256.

  24. Fracanzani, A.L., Burdick, L., Borzio, M., Roncalli, M., Bonelli, N., Borzio, F., Maraschi, A., Fiorelli, G., and Fargion, S. 2001. Contrast-enhanced Doppler ultrasonography in the diagnosis of hepatocellular carcinoma and premalignant lesions in patients with cirrhosis. Hepatology  34: 1109-1112.

  25. Goldberg, S.N., Gazelle, C.S., Compton, C.C., Mueller, P.R., Tanabe, K.K. 2000. Treatment of intrahepatic malignancy with radiofrequency ablation: radiologic-pathologic correlation. Cancer  88: 2452-2463.

  26. Golli, M., Van Nhieu, J.T., Mathieu, D., Zafrani, E.S., Cherqui, D., Dhumeaux, D., Vasile, N. and Rahmouni, A. 1994. Hepatocellular adenoma: Color Doppler US and pathologic correlations. Radiology 190: 741-744

  27. Grazioli, L., Federle, M.P., Ichikawa, T., Balzano, E., Nalesnik, M. and Madariaga, J. 2000. Liver adenomatosis: clinical, histopathologic and imaging findings in 15 patients. Radiology 216: 395-402.

  28. Greis, C. 2004. Technology overview: SonoVue (Bracco, Milan). Eur. Radiol. 14 (Suppl 8): 11-15.

  29. Hamilton, M.F., and Blackstock, D.T. 1998. Nonlinear Acoustics. Academic Press, San Diego, CA.

  30. Harvey, C.J., and Albrecht, T. 2001. Ultrasound of focal liver lesions. Eur. Radiol. 11: 1578-1593.

  31. Harvey, C.J., Blomley, M.J., Eckersley, R.J., Cosgrove, D.O., Patel, N., Heckemann, R.A., and Butler-Barnes, J. 2000. Hepatic malignancies: improved detection with pulse-inversion US in late phase of enhancement with SH U 508A-early experience. Radiology 216: 903-908.

  32. Horiuchi, R., Uchida, T., Kojima, T., and Shikata, T. (1990). Inflammatory pseudotumor of the liver. Clinicalpathological study and review of literature. Cancer 65: 1583-1590.

  33. Howell, J.D., Wotherspoon, H., Leen, E., Cooke, T.C., and MacArlde, C.S. 1999. Evaluation of a follow up programme after curative resection for colorectal cancer. BrJCancer 79: 308-310

  34. Jang, H.J., Choi, B.I., Kim, T.K., Jun, A.J., Kim., K.W., Han, J.K., and Han, M.C. 1998. Atypical small hemangiomas of the liver: “bright dot” sign at two-phase spiral CT. Radiology 208: 543-548.

  35. Ishak, KG., Anthony, PP. and Sobin, LH. 1994. World Health Organization: International Histologic Classification of Tumors, 2nd ed. Berlin, Springer-Verlag.

  36. Iwase, K., Higaki, J., Yoon, HE., Mikata, S., Miyazaki, M., Torikai, K., Shirai,Y., Awai,K., Imakita, M. and Kamiike W. 2002. Solitary necrotic nodule of the liver. J. Hepatobiliary  Pancreat. Surg. 9:120-124.

  37. Karhunen, P.J. 1986. Benign hepatic tumours and tumour-like conditions in men. Clin.Pathol. 39: 183-188.

  38. Kim, C.K., Lim, J.H.,  and Lee, W.J. 2001. Detection of hepatocellular carcinomas and dysplastic nodules in cirrhotic liver: accuracy of ultrasonography in transplant patients. J. Ultrasound Med. 20: 99-104.

  39. Kroncke, T.J., Taupitz, M., Kivelitz, D., Scheer, I., Daberkow, U., Rudolph, B., and Hamm, B. 2000. Multifocal nodular fatty infiltration of the liver mimicking metastatic disease on CT: imaging findings and diagnosis using MR imaging. Eur. Radiol.10:1095-1100.

  40. Leen, E., Angerson, W.J., Yarmenitis, S., Bongartz, G., Blomley, M., Del Maschio, A., Summaria, V., Maresca, G., Pezzoli, C., and Llul, J.B.2002. Multi-centre clinical study evaluating the efficacy of SonoVue (BR1), a new ultrasound contrast agent in Doppler investigation of focal hepatic lesions. Eur. J. Radiology 42: 200-206.

  41. Lencioni, R., Pinto, F., Armillota, N. and Bartolozzi, C. 1996. Assessment of tumor vascolarity in hepatocarcinoma: comparison of power Doppler and Color Doppler US. Radiology 201: 353-358.

  42. Lencioni, R.A., Allgaier, H.P., Cioni, D., Olschewski, M., Deibert, P., Crocetti, L., Frings, H., Laubenberger, J., Zuber, I., Blum, H.E., Bartolozzi, C. 2003. Small hepatocellular carcinoma in cirrhosis: randomized comparison of radiofrequency thermal ablation versus percutanous ethanol injection. Radiology 228: 235-240.

  43. Levine, C. 1990. Primary macronodular hepatic tuberculosis: US and CT appearances. Gastrointest. J.Radiolology 15: 307-309.

  44. Livraghi, T. Role of image-guided therapies in hepatocellular carcinoma.

  45. Livraghi, T., Benedini,V., Lazzaron, S., Meloni, F., Torzilli G., and Vettori C. 1998. Long term results of single session PEI in patients with large hepatocellular carcinoma. Cancer 83: 48-57.

  46. Livraghi, T., Meloni, F., Morabito, A., and Vettori, C. 2004. Multimodal image-guided tailored therapy of early and intermediate hepatocellular carcinoma: long-term survival in the experience of a single radiologic referral center. Liv. Transpl. 10: 98-106.

  47. Matsui, O., Kadoja, M., Kamejama, T., Takashima, T., Nakanuma, J., Unoura, M., Kobayashi, K., Izumi, R., and Ida, M. 1991. Benign and malignant nodules in cirrhotic patients: distinction on blood supply. Radiology 178: 493-497.

  48. Migaleddu, V., Virgilio, G., Campisi, G., Sirigu, D., and Canalis, G.C. 2002. Conventional ultrasonography versus tissue harmonic imaging for the assessment of the common bile duct in cholecystectomized patients. Radiol. Med. 103: 1-6.

  49. Migaleddu, V., Virgilio, G., Turilli, D., Conti, M., Campisi, G., Canu, M., Sirigu, D., and Vincentelli, I. 2004. Charaterization of focal liver lesions in real-time using harmonic imaging with high mechanical index and contrast agent levovist. Am. J. Roentgenol. 182: 1505-1512.

  50. Migaleddu, V., Manca, A., Turilli, D., Luciano, P., Canu, N., Campisi, G., Virgilio, G. 2005. Fundamental nonlinear imaging versus harmonic imaging with contrast medium sonovue in the evaluation of the hepatic focal lesions: preliminary results. Eur. Radiol. 14 (suppl. 1): B-126.

  51. Mirilas, P., and Skandalakis, J.E. 2002. Benign anatomical mistakes: incidentaloma. Am. Surg. 68: 1026-1028.

  52. Moody, A.R., and Wilson, S.R. 1993. Atypical hepatic hemangioma: a suggestive sonographic morphology. Radiology 188: 413-417.

  53. Morel, D.R., Schwieger, I., Hohn, L., Terrettaz. J., Llull, J.B., Cornioley, Y.A., and Schneider, M. 2000. Human Pharmacokinectics and Safety evaluation of SonoVueTM, a new contrast agent for ultrasound imaging. Investigative Radiology 35 1: 80-85.

  54. Nam., K.J., Kang, H.K., and Lim, J.H. 1996. Inflammatory pseudotumor of the liver: CT and sonographic features. Am. J. Roentgenol. 167: 485-487.

  55. Nanda, N.C., and Carstensen, E.L. 1997. Echo-enhancing agents: safety. In: Nanda N.C,. Schlief R and. Goldberg B.B (eds). Advances in Echo Imaging Using Contrast Enhancement, 2nd Ed., 139-170. Kluver Academic Publishers.

  56. Nicolau, C., Vilana, R., and Brù, C. 2004. The use of contrast-enhanced ultrasound in the management of the cirrothic patient and for detection of HCC. Eur. Radiol.14 [Suppl 8]: 63-71.

  57. Nicolau, C., Vilana, R., Catalá, V., Bianchi, L., Gilabert, R., Carcía, A., and Brú, C. 2006. Importance of evaluating all vascular phases on contrast enhanced sonography in the diferentiation of benign from malignant focal lesions. Am. J. Roentgenol. 186: 158-167.

  58. Nordic Gastrointestinal Tumour Adjuvant Therapy Group, 1992. Expectancy or primary chemotherapy in patients with advanced asymptomatic colorectal cancer; a randomisede trial. J. Clinical Oncol. 10: 904-911.

  59. Numata, K., Tanaka, K., Kiba, T., Norimoto, M., Arata, S., Kondo, M., and Sekihara, H. 1997. Use of hepatic tumor index on color Doppler sonography for differentiating large hepatic tumors. Am. J. Roentgenol. 168: 991-995.

  60. Ortega, D., and Burns, P.N., Simpson, D.H., and Wilson, SR. 2001. Tissue Harmionic imaging: is it a benefit for bile duct sonography? Am. J. Roentgenol. 176: 653-659.

  61. Phillips, P., and Gardner, E. 2004. Contrast-agent detection and quantification. Eur. Radiol. 14 (Suppl 8): 4-10.

  62. Powers, J.E., Burns, P.N., and Souquet, J. 1997. Imaging instrumentation for ultrasound contrast agents. In: Nanda, N.C., Schlief, R., and. Goldberg, B.B. (eds). Advances in Echo Imaging Using Contrast Enhancement, 2nd ed, 139-170. Kluver Academic Publishers.

  63. Quaia, E., Calliada, F., Bertolotto, M., Rossi, S., Garioni, L., Rosa, L., and Pozzi-Mucelli, R. 2004. Characterization of focal liver lesions with contrast-specific US modes and a sulfur hexafluoride-filled microbubble contrast agent: diagnostic performance and confidence. Radiology 232: 420-430.

  64. Ros, P., and Davis, G. 1998. The incidental focal liver lesion: Photon, proton, or needle? Hepatology 98: 1183-1190.

  65. Ros, P.R., Menu, Y., Vilgrain, V., Mortele, K.J., and Terris, B. 2001. Liver neoplasms and tumor-like conditions. Eur. Radiol. 11 (Supp 2): 145-165.

  66. Schneider, M., Arditi, M., Barrau, M.B., Brochot, J., Broillet, A., Ventron, R., and Yan, F. 1995. BR1: a new ultrasonographic contrast agent based on sulfur hexafluoride-filled microbubbles. Invest. Radiol. 30: 451-457.

  67. Schwartz, L.H., Gandras, E.J., Colangelo, S.M., Ercolani, M.C., and Panicek, D.M. 1999. Prevalence and importance of small hepatic lesions found at CT in patients with cancer. Radiology 210: 71-74.

  68. Siösteen, A.K., and Elvin, A. 2004. Intra-operative uses of contrast-enhanced ultrasound. Eur. Radiol. 14 (Suppl 8): 87-95.

  69. Solbiati, L., Livraghi, T., Golberg, S.N., Ierace, T., Meloni, F., Dellanoce, M., Cova, L., Halpern, E.F., and Gazelle, G.S. 2001. Percutaneous radio-frequency ablation of liver metastase from colon rectal cancer: long term risults 117 patients. Radiology 221: 159-166.

  70. Solbiati, L., Tonolini, M., and Cova, L. 2004. Monitoring RF ablation. Eur. Radiol. 14 (Suppl 8): 34-42.

  71. Tanaka, S., Ioka, T., Oshikawa, O., Hamada, Y., and Yoshioka, F. 2001. Dynamic sonography of hepatic tumors. Am. J. Roentgenol. 177: 799-805.

  72. Tanaka, S., Kitamura, T., Fuijta, M., Nakanishi, K., and Okuda, S. 1990. Color Doppler flow imaging of liver tumors. Am. J. Roentgenol. 154: 509-514.

  73. Torzilli, G., Del Fabro, D., Palmisano, A., Donadon, M., Bianchi, P., Roncalli, M., Balzarini, L., and Montorsi, M. 2005. Contrast-enhanced intraoperative ultrasonography during hepatectomies for Colon rectal metastaes.  J. Gastrointest. Surgery 9: 1148-1154.

  74. Ueda, K., Terada, T., Nakanuma, Y., and Matsui, O. 1992. Vascular supply in adenomatous hyperplasia of the liver and hepatocellular carcinoma: a morphometric study. Hum. Pathol. 23: 619-626.

  75. Unal, O., Sakarya, M.E., Arslan, H., Tuncer, I., and Etlik, O. 2002. Hepatic cavernous hemangiomas: patterns of contrast enhancement on MR fluoroscopy imaging. Clin. Imag.26: 39-42.

  76. Volk, M., Strotzer, M., Lenhart, M., Techert, J., Seitz, J., and Feuerbach, S. 2001. Frequency of benign hepatic lesions incidentally detected with contrast-enhanced section portal venous pahase spiral CT. Acta Radiol. 42: 172-175.

  77. Ward, B., Baker, AC., and Humprey, VF. 1997. Non linear propagation applied to the improvement of resolution in diagnostic medical ultrasound. J. Acoust. Soc. Am. 101: 143-154.

  78. Ward, J., and Robinson, J. 2002. How to detect hepatocellular carcinoma in chirrhosis. Eur. Radiol. 12: 2258-2272.

  79. Wen, Y.L., Kudo, M., Zheng, R.Q., Ding, H., Zhou, P., Minami, Y., Chung, H., Kitano, M., Kawasaki, T., Maekawa, K. 2004. Characterizazione of hepatic tumors: value of contrast-enhanced coded phase-inversion harmonic angio. Am. J. Roentgenol. 182: 1019-1026.

  80. Zhang, B.H., Yang, B.H., and Tang, Z.Y. 2004. Randomized controll trial of screening for hepatocellular carcinoma. J. Cancer Res. Clin. Onc. 130: 417-422.